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Drug uses
Zyban is a medicine used to help you to give up smoking. It works at the neurological level breaking the dependence on nicotine. The medicine affects the chemicals in the brain called neurotransmitters that are responsible for transmitting messages between the nerve cells. It does not replace one form of nicotine by another one.
How taken
Zyban is available as a tablet taken by mouth. The treatment usually lasts for about 2 months. The average dose to start with is 150 mg daily which may be increased up to 300 mg twice a day. The doses should be taken with an 8-hour-interval (usually in the morning and later, but not at bedtime).The treatment is supposed to be started while you are smoking as the medicine will take about a week to start working, but within a fortnight of treatment you’ll have to give up smoking. The medicine is to be taken as whole and neither chewed or crushed.
1 You are at risk of seizures if you exceed the dose prescribed.
2 Tell the doctor if you have any allergies to any medications or any substances. If you are allergic to the medicine, do not take it any more and consult with your doctor.
3 Do not take Zyban if you are either pregnant or you are breastfeeding. It may do harm to your baby.
4 Control your blood pressure during the treatment.
5 Make sure you know how your body reacts to the medicine before you do anything that may be life-threatening.
6 Make sure your doctor knows about any specific medical conditions of yours such as:
Anxiety disorder
Bipolar illness
Kidney/liver/blood pressure/psychiatric problems
Head injury
7 Tell the doctor about any medications you are taking at the moment. Be sure you’ve mentioned:
MAO inhibitors
Quinolone antibiotics
Slimming medicines
Steroids taken orally or y injection
Any medications containing bupropion
Sedating antihistamines
8 Do not take alcohol during the treatment.
9 Elderly people are more subject to having side effects.
10 Zyban is not recommended for people under 18.
Side effects
Dryness in the mouth, giddiness, flu-like symptoms, pain in the stomach, chest, sore throat, anxiety, headache, rash, excitement, vision problems, sleep disturbance, sweating, mania, priapism (permanent and painful erection) may be observed during the treatment. There is some risk of seizures, social thoughts and behavior problems (in children) as well. Make sure the doctor knows if any side effects occur.
Missed dose
Do not make up for a missed dose. Follow your everyday schedule.
Cases of overdose have been observed when up to 30g were taken. The signs of overdose are arrhythmias, hallucinations, stupor, respiratory problems, sinus tachycardia, hypotension, muscle rigidity, conduction disturbance, fainting and coma. Call the emergency if the overdose is suspected.
  • Keep way from children
  • Sore at room temperature
  • Keep away from moisture, heat, cold and direct light
  • Dispose of an outdated medicine

This information is to serve your information purposes only and not to substitute for the knowledge and skills of your healthcare practitioner. It covers only the general issues of the drug uses, direction, warning and possible side effects and is not to be looked upon as an instruction for a particular patient. We disclaim all responsibility for any adverse effects or any negative consequences that may be the result of the use of this information.